Assignment First

美国代写论文:聚合物胶束的药物策略

化疗不被认为是一个好的选择,因为它对健康的不良影响。这是由低水平的生物利用度以及耐药性的发展和出现支持的。几份报告指出,对多种药物的耐药性将显著限制抗癌药物对肿瘤组织的渗透。这导致肿瘤内抗癌药物浓度低,进一步导致化疗失败。为了克服这些局限性,利用各种生物相容性纳米材料设计了一些具有有效进展的药物传递系统。一种最有前途的药物策略是聚合物纳米微球系统,该系统已经在许多试验中得到应用。与其他药物输送系统相比,聚合物胶束具有生产效率低、循环时间长、靶向性强等优点。

美国代写论文:聚合物胶束的药物策略

此外,还将对诱捕的抗癌药物在生物介质中的失活提供特殊保护。这是因为聚合物胶束体系中核心壳层的特殊结构。从总体上看,聚合物胶束是一种很好的纳米给药系统。虽然聚合物胶束对纳米药物抗癌传递体系的建立有着显著影响,但在某些方面仍有改进的空间。这是因为人类40%的肿瘤具有对化疗药物产生耐药性的能力。

美国代写论文:聚合物胶束的药物策略

Chemotherapy is not considered a good option because of its undesirable negative implications on the health. This is supported by low level of bioavailability along with the development and emergence of drug resistance. Several reports have stated that resistance to multiple drugs will be significantly limiting the penetration in tumor tissues by anti-cancer drugs. This leads towards poorly concentrated anti-cancer drugs inside the tumor which further fails the procedure of chemotherapy. For the purpose of overcoming these limitations, a number of drug delivery systems with effective advancement are designed by the use of various biocompatible nano-materials. A pharmaceutical strategy that is most promising is the system of polymeric nanomicelle that has been applied in a number of trials. Polymeric micelles are known for exhibiting various benefits in comparison with other delivery systems of drug like eased production, longer circulation and ability of targeting.

美国代写论文:聚合物胶束的药物策略

In addition, specific protection will be provided to entrapped drugs of anti-cancer from inactivation in the media of biology. This is because of the specific structure of core shell across the system of polymeric micelle. In collective terms, it has been discovered that polymeric micelles are excellent system of nano-drug delivery for chemotherapy. Even though polymeric micelles are known for significantly affecting the establishment of anti-cancer delivery systems loaded with nano drugs, there is a scope of improvement in certain aspect. This is because 40 per cent of tumors in humans have the ability of developing resistance against agents of chemotherapy.